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SUMMARY:GDCh-Kolloquium: Prof. Dr.  Hiroaki Suga
DTSTART;TZID=Europe/Berlin:20261021T171500
DTEND;TZID=Europe/Berlin:20261021T190000
DTSTAMP:20260929T190628Z
UID:19c0c3b54af54035a4a5274d1cf14260@www.chemie.uni-bonn.de
CATEGORIES:GDCh-events,fg-events,tc-seminar,pc-events,oc-events,ac-events
CREATED:20260928T094246Z
DESCRIPTION:Prof. Dr. Hiroaki Suga\, The University of Tokyo\, Department 
 of Chemistry: \n\nGenetic Code Reprogramming by flexizymes for Therapeutic
  Innovation\n\nGenetic code reprogramming is the method to redesign the ge
 netic code restricted by 20 pro-teinogenic amino acids with other exotic b
 uilding blocks. Although there are some ways to re-program the genetic cod
 e\, flexizymes invented by Suga and colleagues are highly versatile cata-l
 ysts to charge a wide range of such amino acids\, including D-amino acids\
 , beta/gamma-amino acids\, and hydroxy acids. The combination of flexizyme
  technology with a custom-made cell-free translation system\, referred to 
 as Flexible In-vitro Translation (FIT) system\, enables for ex-pression of
  libraries of nonstandard peptides containing exotic building blocks. This
  method is further integrated with mRNA display has led to the invention o
 f RaPID (Random nonstandard Peptides Integrated Discovery) system\, giving
  ultrafast discovery of de novo bioactive peptides.
LAST-MODIFIED:20260928T094301Z
URL:https://www.chemie.uni-bonn.de/de/gdch/gdch-events/gdch-kolloquium-pro
 f-dr-hiroaki-suga
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