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SUMMARY:OC-Seminar: Jun.-Prof. Dr. J. Walker\, University of Göttingen
DTSTART;TZID=Europe/Berlin:20251216T110000
DTEND;TZID=Europe/Berlin:20251216T120000
DTSTAMP:20260603T003422Z
UID:5ee6c89ccb424039937ae337705f6790@www.chemie.uni-bonn.de
CATEGORIES:oc-events
CREATED:20251010T095544Z
DESCRIPTION:Jun.-Prof. Dr. Johannes C. L. Walker\, University of Göttinge
 n:\nPhotochemical and Stereoselective Approaches to Bridged Bicyclic Archi
 tectures\n\nSaturated\, polycyclic structures are in high demand as novel 
 building blocks in drug discovery programmes.Their greater number of satur
 ated\, sp3-hybridised carbon atoms has been associated with an improved aq
 ueous solubility and metabolic stability compared to their unsaturated\, b
 enzene-based analogues. Structurally rigid examples such as bicyclo[1.1.1]
 pentanes have been proposed as bioisosteres of para-substituted benzenes b
 ut the numerous exit vectors of these and related polycyclic structures pr
 esent additional opportunities for accessing untapped chemical space. Desp
 ite the potential breadth of application of these types of compounds\, fle
 xible\, and particularly stereoselective\, approaches for the synthesis of
  polysubstituted bridged bicyclic motifs remain relatively rare.
LAST-MODIFIED:20251014T130404Z
URL:https://www.chemie.uni-bonn.de/oc/de/veranstaltungen/oc-seminar-jun-pr
 of-dr-j-walker-university-of-goettingen
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