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The Biophysical Chemistry Workgroup

3D-Tracking

mRNA-Export


Our work group is devoted to the analysis of molecular dynamics in the context of biological or biomimetical systems; our core area is the analysis of molecular kinetics within supra-molecular complexes on the single molecule level.

We employ state-of-the-art light microscopy techniques like confocal scanning microscopy and single-molecule microscopy using different illumnation techniques.

Our labs are equipped for the preparatory biochemistry and all standard protocols from cell to molecular biology.

A further key aspect of our work is the development of new or the improvement of existing light microscopic methods; current emphases are light sheet fluorescence microscopy (LSFM), confocal LSFM and 3D particle tracking.


Latest
Publication:

 Whole-brain 3D mapping

 of human neural transplant innervation

"... Rabies virus-based retrograde tracing has developed into a powerful approach for visualizing synaptically connected neurons. Here, we combine this technique with light sheet fluorescence microscopy (LSFM) to visualize transplanted cells and connected host neurons in whole-mouse brain preparations. ..."NatureComm2017
 http://www.nature.com/articles/ncomms14162
  

 

 

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